Princeton University Library Catalog

Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology / edited by Chao Han, Charles B. Davis, Binghe Wang.

Format:
Book
Language:
English
Published/​Created:
Hoboken, N.J. : John Wiley & Sons, c2010.
Description:
x, 289 p., [2] p. of plates : ill. (some col.) ; 25 cm.
Bibliographic references:
Includes bibliographical references and index.
Contents:
Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.
Subject(s):
ISBN:
  • 9780470044919 (cloth)
  • 0470044918 (cloth)
LCCN:
2009035876
OCLC:
435728364
Related name:
RCP:
C - S