Bull's-eye : unraveling the medical mystery of Lyme disease / Jonathan A. Edlow.

Edlow, Jonathan A. [Browse]
New Haven : Yale University Press, c2003.
xviii, 285 p. : ill. ; 25 cm.


Lyme diseaseHistory [Browse]
Summary note
  • "Jonathan Edlow, M.D., begins his detective story in Lyme, Connecticut, with the accounts of two housewives who in the mid-1970s noticed a baffling array of symptoms afflicting members of their families and others in the community. As physicians studied this strange disease they unearthed similar symptoms that were reported long ago in other countries - such as rashes in Sweden and confusing neurological syndromes in France and Germany in the early 1900s.
  • Edlow's account also unravels the medical and social issues that accompanied research efforts into this new disease as he reviews lessons learned from other baffling cases, such as the dreaded cholera outbreak in 1854 in London, and the efforts to prevent childbirth fever in Vienna in 1846.".
  • "Edlow chronicles how connections were ultimately established between symptoms and tick bites, leading to the discovery of the stages of the disease, its specific microbial cause, and its treatment. And he brings the story into the twenty-first century by discussing legal and legislative issues, as well as factors that have led to recent widespread outbreaks of Lyme disease and to the controversies over its diagnosis, vaccine, treatment, and even its very definition."--BOOK JACKET.
Bibliographic references
Includes bibliographical references (p. 259-274) and index.
1. A Family Under Siege -- 2. A Little Girl's Knee -- 3. The Broad Street Pump -- 4. An Appointment in New Haven -- 5. An Outbreak of Arthritis -- 6. An Outbreak of Dermatitis -- 7. The European Connection -- 8. Further Work in Europe -- 9. The Blind Men and the Elephant -- 10. The Connection with Ticks -- 11. An Intersection of Investigations -- 12. From the Alps to the Rockies -- 13. To Treat or Not to Treat? -- 14. The Scramble for the Cause -- 15. The Culmination of Efforts -- 16. Progress to the End of the 1980s -- 17. A Geographical Expansion -- 18. The Diagnostician's Dilemma -- 19. Ambiguity in the Lab -- 20. A Tick with Two Toxins -- 21. Cracks in the Theory -- 22. Another Paradigm -- 23. Therapeutic Adventures -- 24. Genomes and Vaccines -- 25. Legal and Political Battles -- 26. An Independent Reality -- App. A. Symptoms of Lyme Disease -- App. B. Tick-Borne Diseases in Humans and Animals.
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