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Princeton University Library Catalog
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DNA repair in cancer therapy : molecular targets and clinical applications / edited by Mark R. Kelley.
Format
Book
Language
English
Εdition
1st ed.
Published/Created
Amsterdam ; Boston : Academic Press, 2012.
Description
xiii, 316 pages : illustrations ; 29 cm
Availability
Copies in the Library
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Call Number
Status
Location Service
Notes
ReCAP - Remote Storage
RC270.8 .D53 2012 Q
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Details
Subject(s)
Cancer
—
Treatment
—
Genetic aspects
[Browse]
DNA repair
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Related name
Kelley, Mark R., 1961-
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Bibliographic references
Includes bibliographical references and index.
Contents
Introduction and overview of current targets: bench to clinic / Mark R. Kelley
2. MGMT a critical DNA repair gene target for chemotherapy resistance / Stanton L. Gerson and Lili Liu
3. Blockade of base excision repair: inhibition of small lesions results in big consequences to cancer cells / Melissa Fishel and Carlo Vascotto
4. PARP inhibitors - scientific rationale and clinical development for cancer / Ruth Plummer, Nicola J. Curtin and Yvette Drew
5. inhibiting selective DNA polymerases for therapeutic intervention / Anthony J. Berdis
6. Targeting the nucleotide excision repair pathway for therapeutic applications / John Turchi and Stephan M. Patrick
7. Homologous recombination and ATM/ATR targets / Henning Willers, Lee Zou and Heike N. Pfaffle
8. DNA double strand break repair by nonhomologous end joining and its clinical relevance / Michael Weinfeld and Susan Lees-Miller
9. Defective MMR-c-Abl-p73-GADD45alpha expression in cancer chemoresistance / David Boothman and Long Shan Li
10. DNA repair signaling targets / Susan Ashwell
11. Redox regulation of DNA repair and therapeutic / Millie M. Georgiadis
12. Personalized cancer medicine: DNA repair alterations is a promising predictive marker in cancer / Srinivasan Madhusudan
13. The role of DNA damage and repair in neurotoxicity caused by cancer therapies / Michael R. Vasko
14. Future directions with DNA repair inhibitors / Mark R. Kelley.
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ISBN
9780123849991
0123849993
OCLC
711573687
RCP
C - S
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