Princeton University Library Catalog

Sample sizes for clinical trials / Steven A. Julious.

Author:
Julious, Steven A. [Browse]
Format:
Book
Language:
English
Published/​Created:
Boca Raton : CRC Press/Taylor & Francis, c2010.
Description:
xxvii, 299 p. : ill. ; 25 cm.
Summary note:
"Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis." "Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including superiority, equivalence, non-inferiority, bioequivalence, and precision for both parallel group and cross-over designs. The author discusses how trial objectives impact the study design with respect to the derivation of formulae for sample size calculations. He uses real-life studies throughout to show how the concepts and calculations can be employed."--BOOK JACKET.
Bibliographic references:
Includes bibliographical references and index.
Contents:
1. Introduction -- 2. Seven Key Steps to Cook Up a Sample Size -- 3. Sample Sizes for Parallel Group Superiority Trials with Normal Data -- 4. Sample Size Calculations for Superiority Cross-over Trials with Normal Data -- 5. Sample Size Calculations for Equivalence Clinical Trials with Normal Data -- 6. Sample Size Calculations for Non-Inferiority Clinical Trials with Normal Data -- 7. Sample Size Calculations for Bioequivalence Trials -- 8. Sample Size Calculations for Precision-Based Clinical Trials with Normal Data -- 9. Sample Size Calculations for Parallel Group Superiority Clinical Trials with Binary Data -- 10. Sample Size Calculations for Superiority Cross-over Clinical Trials with Binary Data -- 11. Sample Size Calculations for Non-inferiority Trials with Binary Data -- 12. Sample Size Calculations for Equivalence Trials with Binary Data -- 13. Sample Size Calculations for Precision-Based Trials with Binary Data -- 14. Sample Size Calculations for Clinical Trials with Ordinal Data -- 15. Sample Size Calculations for Clinical Trials with Survival Data.
Subject(s):
ISBN:
  • 9781584887393 (hardcover : alk. paper)
  • 1584887397 (hardcover : alk. paper)
LCCN:
2008053599
OCLC:
288983232
RCP:
C - S