Details

Subject(s)

• Clinical trials—Statistical methods [Browse]
• Sampling (Statistics) [Browse]

Summary note

"Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis." "Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including superiority, equivalence, non-inferiority, bioequivalence, and precision for both parallel group and cross-over designs. The author discusses how trial objectives impact the study design with respect to the derivation of formulae for sample size calculations. He uses real-life studies throughout to show how the concepts and calculations can be employed."--BOOK JACKET.

Bibliographic references

Includes bibliographical references and index.

Contents

• 1. Introduction
• 2. Seven Key Steps to Cook Up a Sample Size
• 3. Sample Sizes for Parallel Group Superiority Trials with Normal Data
• 4. Sample Size Calculations for Superiority Cross-over Trials with Normal Data
• 5. Sample Size Calculations for Equivalence Clinical Trials with Normal Data
• 6. Sample Size Calculations for Non-Inferiority Clinical Trials with Normal Data
• 7. Sample Size Calculations for Bioequivalence Trials
• 8. Sample Size Calculations for Precision-Based Clinical Trials with Normal Data
• 9. Sample Size Calculations for Parallel Group Superiority Clinical Trials with Binary Data
• 10. Sample Size Calculations for Superiority Cross-over Clinical Trials with Binary Data
• 11. Sample Size Calculations for Non-inferiority Trials with Binary Data
• 12. Sample Size Calculations for Equivalence Trials with Binary Data
• 13. Sample Size Calculations for Precision-Based Trials with Binary Data
• 14. Sample Size Calculations for Clinical Trials with Ordinal Data
• 15. Sample Size Calculations for Clinical Trials with Survival Data.

Show 12 more Contents items

ISBN

• 9781584887393 (hardcover : alk. paper)
• 1584887397 (hardcover : alk. paper)

LCCN

2008053599

OCLC

288983232

RCP

C - S

Statement on language in description

Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage. Read more...