Adaptive design methods in clinical trials / Shein-Chung Chow, Mark Chang.

Author
Chow, Shein-Chung, 1955- [Browse]
Format
Book
Language
English
Εdition
2nd ed.
Published/​Created
Boca Raton, FL : CRC Press, c2012.
Description
xvi, 358 p. : ill. ; 25 cm.

Details

Subject(s)
Related name
Series
Chapman & Hall/CRC biostatistics series. [More in this series]
Notes
"A Chapman & Hall book."
Bibliographic references
Includes bibliographical references and index.
Contents
Protocol amendment -- Adaptive randomization -- Adaptive hypotheses -- Adaptive dose-escalation trials -- Adaptive group sequential design -- Statistical tests for adaptive seamless designs -- Adaptive sample size adjustment -- Two-stage adaptive design -- Adaptive treatment switching -- Bayesian approach -- Biomarker adaptive trials -- Target clinical trials -- Sample size and power estimation -- Clinical trial simulation -- Regulatory perspectives : a review of FDA draft guidance.
ISBN
  • 9781439839874 (hardcover : alk. paper)
  • 1439839875 (hardcover : alk. paper)
LCCN
2011046596
OCLC
761361235
RCP
C - S