Princeton University Library Catalog

Characterization of nanoparticles intended for drug delivery / edited by Scott E. McNeil.

Format:
Book
Language:
English
Published/​Created:
New York, N.Y. : Humana Press, c2011.
Description:
xii, 269 p. : ill. (some col.) ; 26 cm.
Series:
Bibliographic references:
Includes bibliographical references and index.
Contents:
Unique benefits of nanotechnology to drug delivery and diagnostics -- Challenges for nanoparticle characterization -- Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review -- Measuring the hydrodynamic size of nanoparticles in aqueous media using batch-mode dynamic light scattering -- Characterization of nanoparticles by matrix assisted laser desorption ionization time-of-flight mass spectrometry -- Zeta potential measurement -- Size measurement of nanoparticles using atomic force microscopy -- Biological tissue and cell culture specimen preparation for TEM nanoparticle characterization -- SEM x-ray microanalysis of nanoparticles present in tissue or cultured cell thin sections -- Detecting and measuring free gadolinium in nanoparticles for MRI imaging -- Lipid component quantitation by thin layer chromatography -- Detection and quantitative evaluation of endotoxin contamination in nanoparticle formulations by LAL-based assays -- Analysis of microbial contamination in nanoparticle formulations -- Gold nanoparticle quantitation via fluorescence in solution and cell culture -- Quantitation of nanoparticles in serum matrix by capillary electrophoresis -- Evaluation of cytotoxicity of nanoparticulate materials in porcine kidney cells and human hepatocarcinoma cells -- Monitoring nanoparticle-treated hepatocarcinoma cells for apoptosis -- Detecting reactive oxygen species in primary hepatocytes treated with nanoparticles -- Assay to detect lipid peroxidation upon exposure to nanoparticles -- Monitoring glutathione homeostasis in nanoparticle-treated hepatocytes -- Autophagy monitoring assay: Qualitative analysis of MAP LC3-I to II conversion by immunoblot -- Monitoring lysosomal activity in nanoparticle-treated cells -- Method for analysis of nanoparticle hemolytic properties in vitro -- Method for in vitro analysis of nanoparticle thrombogenic properties -- Qualitative analysis of total complement activation by nanoparticles -- Method for analysis of nanoparticle effects on cellular chemotaxis -- In vitro analysis of nanoparticle uptake by macrophages using chemiluminescence.
Subject(s):
ISBN:
  • 9781603271974 (hbk.)
  • 9781603271981
  • 1603271988
OCLC:
694899396
Related name:
RCP:
C - S