Fetal and neonatal brain injury / edited by David K. Stevenson ... [et al.].

4th ed.
Cambridge, UK ; New York : Cambridge University Press, 2009.
xiii, 628 p., [8] p. of plates : ill. (some col.) ; 29 cm.


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Bibliographic references
Includes bibliographical references and index.
  • Section 1. Epidemiology, pathophysiology, and pathogenesis of fetal and neonatal brain injury -- Neonatal encephalopathy: epidemiology and overview -- Mechanisms of neurodegeneration and therapeutics in animal models of neonatal hypoxic-ischemic encephalopathy -- Cellular and molecular biology of hypoxic-ischemic encephalopathy -- The pathogenesis of preterm brain injury -- Section 2. Pregnancy , labor, and delivery complications causing brain injury -- Prematurity and complication s of labor and delivery -- Risks and complications of multiple gestations -- Intrauterine growth restriction -- Maternal diseases that affect fetal development -- Obstetrical conditions and practices that affect the fetus and newborn -- Fetal and neonatal injury as a consequence of maternal substance abuse -- Hypertensive disorders of pregnancy -- Complications of labor and delivery -- Fetal response to asphyxia -- Antepartum evaluation of fetal well-being -- Intrapartum evaluation of the fetus -- Section 3. Clinical manifestations of hypoxic-ischemic encephalopathy -- The use of EEG in assessing acute and chronic brain damage in the newborn -- Neuroimaging in the evaluation of pattern and timing of fetal and neonatal brain abnormalities -- Light-based functional assessment of the brain -- Placental pathology and the etiology of fetal and neonatal brain injury -- Correlations of clinical, laboratory, imaging, and placental findings as to the timing of asphyxial events --
  • Section 4. Specific conditions associated with fetal and neonatal brain injury -- Congenital malformation s of the brain -- Neurogenetic disorders of the brain -- Hemorrhagic lesions of the central nervous system -- Neonatal stroke -- Hypoglycemia in the neonate -- Hyperbilirubinemia and kernicterus -- Polycythemia and fetal-maternal bleeding -- Hydrops fetalis -- Bacterial sepsis in the neonate -- Neonatal bacterial meningitis -- Neurological sequelae of congenital perinatal infection -- Perinatal human immunodeficiency virus infection -- Inborn errors of metabolism with features of hypoxic-ischemic encephalopathy -- Acidosis and alkalosis -- Meconium staining and the meconium aspiration syndrome -- Persistent pulmonary hypertension of the newborn -- Pediatric cardiac surgery: relevance to fetal and neonatal brain injury -- Section 5. Management of the depressed or neurologically dysfunctional neonate -- Neonatal resuscitation: immediate management -- Improving performance, reducing error, and minimizing risk in the delivery room -- Extended management following resuscitation -- Endogenous and exogenous neuroprotective mechanisms after hypoxic-ischemic injury -- Neonatal seizures: and expression of fetal or neonatal brain disorders -- Nutritional support of the asphyxiated infant -- Section 6. Assessing outcome of the brain-injured infant -- Early childhood neurodevelopmental outcome of preterm infants -- Cerebral palsy: advances in definition, classification, management, and outcome -- Long-term impact of neonatal events on speech, language development, and academic achievement -- Neurocognitive outcomes of term infants with perinatal asphyxia -- Appropriateness of intensive care application -- Medicolegal issues in perinatal brain injury.
  • 9780521888592 (hardback)
  • 052188859X (hardback)
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