Princeton University Library Catalog

Gene discovery for disease models / edited by Weikuan Gu.

Format:
Book
Language:
English
Published/​Created:
Hoboken, N.J. : Wiley, c2011.
Description:
xiii, 537 p. : ill. (some col.) ; 25 cm.
Bibliographic references:
Includes bibliographical references and index.
Contents:
Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.
Subject(s):
ISBN:
  • 9780470499467 (cloth)
  • 047049946X (cloth)
LCCN:
2010028355
OCLC:
646388483
Related name:
RCP:
C - S