Princeton University Library Catalog

The urinary proteome : methods and protocols / edited by Alex J. Rai.

[Totowa, N.J.] : Humana Press, c2010.
xi, 361 p. : ill. (some col.) ; 26 cm.
Summary note:
"Urine is one of the most easily accessible biological samples, and it provides a treasure trove of molecules essential for clinical diagnostics. In The Urinary Proteome: Methods and Protocols, expert researchers review briefly the classical urine tests that are performed in the clinical laboratory and then delve into the state of the art methods for proteomic analysis using urine specimens. Featuring the most recent advances in sample preparation, data analysis, and methods and applications, the book contains a multitude of detailed methods, including procedural details for the identification and characterization of urine biomarkers, which hold great potential for the diagnosis and treatment of many different disease conditions. Written in the highly successful Methods in Molecular Biology" series format, chapters present brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes highlighting tips on troubleshooting and avoiding known pitfalls." "Authoritative and systematic, The Urinary Proteome: Methods and Protocols is an ideal guide for scientific researchers, clinical laboratorians, clinical and translational scientists, and others interested in the vital study of proteomics and biomarker discovery."--BOOK JACKET.
Bibliographic references:
Includes bibliographical references and index.
1. Introduction to Urinalysis: Historical Perspectives and Clinical Application / German Echeverry and Glen L. Hortin -- 2. A Primer on Clinical Applications and Assays Using Urine: Focus on Analysis of Plasma Cell Dyscrasias Using Automated Electrophoresis and Immunofixation / Alex J. Rai and Brianne Olivier -- 3. Application of Free Flow Electrophoresis to the Analysis of the Urine Proteome / Alex J. Rai, Aside L. Foucber and David R. Craft -- 4. Standardized Preprocessing of Urine for Proteome Analysis / Craig A. Gelfand, Georg Martin Fiedler, Uta Ceglarek and Alexander Leichtle -- 5. Different Sample Preparation and Detection Methods for Normal and Lung Cancer Urinary Proteome Analysis / Joachim Thiery, Supackok Sincbaikul, Payungsak Tantipaiboonwong, Supawadee Sriyam, Ching Tzao and Suree Phutrakul -- 6. Isolation and Purification of Exosoines in Urine / Sbui-Tein Chen, Patricia A. Gonzales, Hua Zbou, Trairak Pisitkun, Nam Sun Wang, Robert A. Star and Mark A. Knepper -- 7. Bioinformatics of the Urinary Proteome / Peter S.T. Yuen and Laurence D. Parnell -- 8. PROTIS: Use of Combined Biomarkers for Providing Diagnostic Information on Disease States / Christine M.E. Schueller, Walter Hofmann, Cornelia Sedlmeir-Hofmann, Miroslav Ivandic and Dagmar Ruth -- 9. Statistical Contributions to Proteomic Research / Peter Luppa, Jeffrey S. Morris, Keith A. Baggerly and Howard B. Gutstein -- 10. A Review of Experimental Design Best Practices for Proteomics Based Biomarker Discovery: Focus on SELDI-TOF / Kevin R. Coombes -- 11. Urine Proteomic Profiling for Biomarkers of Acute Renal Transplant Rejection / Rebecca E. Caffrey and Sbu-Ling Liang -- 12. Surface Plasmon Resonance Biosensorics in Urine Proteomics / William Clarke, Peter B. Luppa and Jochen Metzger -- 13. Urinary Proteins for the Diagnosis of Obstructive Sleep Apnea Syndrome / Heike Schneider, Ayelet Snow, David Gozal and Roland Valdes Jr. -- 14. Immune Response Biomarker Profiling Application on ProtoArrayư Protein Microarrays / Saeed A. Jortani, Barry Schweitzer, Libao Meng and Dawn Mattoon -- 15. Design and Validation of an Immunoaffinity LC-MS/MS Assay for the Quantification of a Collagen Type II Neoepitope Peptide in Human Urine: Application as a Biomarker of Osteoarthritis / Alex J. Rai, Olga Nemirovskiy and Wenlin Wendy Li -- 16. Cell-Specific Biomarkers in Renal Medicine and Research / Gabriella Szekely-Klepser -- 17. Proteomic Assays for the Detection of Urothelial Cancer / Martin Shaw and Kris B. Gaston -- 18. Urine Proteomic Analysis: Use of Two-Dimensional Gel Electrophoresis, Isotope Coded Affinity Tags, and Capillary Electrophoresis / H. Barton Grossman -- 19. Proteomic Analysis of Pancreatic Secretory Trypsin Inhibitor/Tumor-Associated Trypsin Inhibitor from Urine of Patients with Pancreatitis or Prostate Cancer / Kimia Sobhani, Leena Valmu and Suvi Ravela.
Laboratory Manuals
  • 9781607617105 (hbk.)
  • 1607617102 (hbk.)
  • 1607617110 (e-ISBN)
  • 9781607617112 (e-ISBN)
Related name:
C - S