Princeton University Library Catalog

Protein misfolding and cellular stress in disease and aging : concepts and protocols / edited by Peter Bross, Niels Gregersen.

Format:
Book
Language:
English
Published/​Created:
Totowa, N.J. : Humana ; London : Springer [distributor], 2010.
Description:
xi, 330 p. : ill. ; 27 cm.
Series:
Bibliographic references:
Includes bibliographical references and index.
Contents:
Part I. Concepts -- 1. Protein Misfolding and Cellular Stress: An Overview / Peter Bross -- 2. Protein Aggregation Diseases: Toxicity of Soluble Prefibrillar Aggregates and Their Clinical Significance / Massimo Stefani -- 3. Consequences of Stress in the Secretary Pathway: the ER Stress Response and Its Role in the Metabolic Syndrome / Louise Sutcliffe -- 4. What Role Does Mitochondrial Stress Play in Neurodegenerative Diseases? / Carlos Torres Moraes -- 5. Autophagy in Disease / Rodney J. Devnish -- 6. Mitophagy and Mitoptosis in Disease Processes / Rodney J. Devnish -- 7. Cellular Stress and Protein Misfolding During Aging / Suresh I.S. Rattan -- 8. Measuring Consequences of Protein Misfolding and Cellular Stress Using OMICS Techniques / Niels Gregersen -- Part II. Protocols -- 9. Production of Cells with Targeted Integration of Gene Variants of Human ABC Transporter for Stable and Regulated Expression Using the Flp Recombinase System / Toshihisa Ishikawa -- 10. Stress Response Profile in Human Fibroblasts Exposed to Heat Shock or Oxidative Stress / Niels Gregersen -- 11. Examining Ubiquitinated Protein Aggregates in Tissue Sections / John H. Brumell -- 12. Determination of Proteasomal Activities / Suresh I. S. Rattan -- 13. Measurement of Autophagy in Cells and Tissues / Satoshi Waguri -- 14. Transcription Factor Sequestrational by Polyglutamine Proteins / Nobuyuki Nukina -- 15. Biological Membranes as Protein Aggregation Matrices and Targets of Amyloid Toxicity / Cristina Cecchi -- 16. Measurement of Mitochondrrial ROS Production / Anatoly A. Starkov -- 17. In Vivo Detection of Oxidized Proteins: A Practical Approach to Tissue-Derived Mitochondria / Giorgio Casari -- 18. Measurement of Oxidized/Reduced Glutathione Ratio / D. Allan Butterfield -- 19. Determination of Altered Mitochondria Ultrastructure by Electron Microscopy / Shoichi Sasaki -- 20. Assessing Bad Sub-cellular Localization Under Conditions Associated with Prevention or Promotion of Mitochondrial Permeability Transition-Dependent Toxicity / Orazio Cantoni -- 21. A Cellular Viability Assay to Monitor Drug To Monitor Drug Toxicity / Peter Bross -- 22. Rescue of Misfolded Proteins and Stabilization by Small Molecules / Aurora Martinez.
Subject(s):
ISBN:
  • 9781607617556 (hbk.)
  • 1607617552 (hbk.)
OCLC:
636917493
Related name:
RCP:
C - S