Princeton University Library Catalog

Alzheimer's disease and frontotemporal dementia : methods and protocols / edited by Erik D. Roberson.

Format:
Book
Language:
English
Published/​Created:
Totowa, N.J. : Humana ; London : Springer [distributor], 2011.
Description:
x, 277 p. : ill. (some col.) ; 27 cm.
Series:
Contents:
1. Contemporary Approaches to Alzheimer's Disease and Frontotemporal Dementia / Erik D. Roberson -- PART I. WORKING WITH AD-AND FTD-RELATED MOLECULES -- 2. Preparing Synthetic Aβ in Different Aggregation States / Mary Jo LaDu -- 3. Isolation of Low-n Amyloid β-Protein Oligomers from Cultured Cells, CSF, and Brain / Dominic M. Walsh -- 4. Detecting Aβ56 Oligomers in Brain Tissues / Sylvain E. Lesne -- 5. Assessing Aβ Aggregation State by Atomic Force Microscopy / Justin Legleiter -- 6. Measuring APP Carboxy-Terminal Fragments / Luke A. Esposito -- 7. Detection of APP Intracellular Domain in Brain Tissue / Anupama Suryanarayana -- 8. Cell-Based Assays for Regulators of Tau Biology / Chad A. Dickey -- 9. Split GFP Complementation Assay for Quantitative Measurement of Tau Aggregation In Situ / Gail V. W. Johnson -- 10. Apolipoprotein E. Expression and Purification / Karl H. Weisgraber -- PART II. MODEL SYSTEMS AND OUTCOME MEASURES -- 11. Aβ Toxicity in Primary Cultured Neurons / Sara Kleinschmidt -- 12. Manipulation of Gene Expression in the Central Nervous System with Lentiviral Vectors / Li Gan -- 13. Selecting a Mouse Model of Alzheimer's Disease / Jeannie Chin -- 14. Monitoring Spatial Learning and Memory in Alzheimer's Disease Mouse Models Using the Morris Water Maze / Kimberly Scearce-Levie -- 15. Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain / Inma Cobos -- 16. Real-Time Visualization of Axonal Transport in Neurons / Bianxiao Cui -- 17. Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer's Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling / Erik D. Roberson -- 18. Epigenetic Changes in the Brain: Measuring Global Histone Modifications / Courtney A. Miller.
Subject(s):
ISBN:
  • 9781607617433 (hbk.)
  • 1607617439 (hbk.)
OCLC:
659242931
Related name:
RCP:
C - S