The networking of chaperones by co-chaperones : control of cellular protein homeostasis / Gregory Lloyd Blatch, Adrienne Lesley Edkins, editors.

[2nd updated and enlarged edition]
  • Cham [Switzerland] : Springer, [2015]
  • ©2015
xv, 276 pages : illustrations (chiefly color) ; 24 cm


Summary note
"Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology"--Publisher's website.
Includes bibliographical references and index.
Bibliographic references
Includes bibliographical references and index.
  • GrpE, Hsp110-Grp170, HspBP1/Sil1 and BAG domain proteins: nucleotide exchange factors for Hsp70 molecular chaperones / Andreas Bracher and Jacob Verghese
  • Functions of the Hsp90-binding FKBP immunophilins / Naihsuan C. Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana and Marc B. Cox
  • Hsp70/Hsp90 organising protein (Hop): beyond interactions with chaperones and prion proteins / Swati Baindur-Hudson, Adrienne L. Edkins and Gregory L. Blatch
  • Specification of Hsp70 function by type I and type II Hsp40 / Douglas M. Cyr and Carlos H. Ramos
  • Cdc37 as a co-chaperone to Hsp90 / Stuart K. Calderwood
  • p23 and Aha1 / Alexandra Beatrice Rehn and Johannes Buchner
  • UCS proteins: chaperones for myosin and co-chaperones for Hsp90 / Weiming Ni and Odutayo O. Odunuga
  • Chaperonin-co-chaperonin interactions / Aileen Boshoff --Co-chaperones of the mammalian endoplasmic reticulum / Armin Melnyk, Heiko Rieger and Richard Zimmermann
  • The evolution and function of co-chaperones in mitochondria / Neta Regev-Rudzki, Kip Gabriel and Dejan Bursac
  • CHIP: a co-chaperone for degradation by the proteasome / Adrienne L. Edkins
  • The role of HSP70 and Its co-chaperones in protein misfolding, aggregation and disease / Emma J. Duncan, Michael E. Cheetham, J. Paul Chapple and Jacqueline van der Spuy.
  • 9783319117300 ((hardback : alk. paper))
  • 3319117300 ((hardback : alk. paper)
Statement on language in description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage. Read more...
Other views
Staff view

Supplementary Information