Details

Subject(s)

• Molecular chaperones [Browse]
• Homeostasis [Browse]

Editor

• Blatch, Gregory L. [Browse]
• Edkins, Adrienne Lesley [Browse]

Series

• Sub-cellular biochemistry ; v. 78. [More in this series]
• Sub-cellular biochemistry ; 0306-0225, volume 78 [More in this series]

Summary note

"Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology"--Publisher's website.

Notes

Includes bibliographical references and index.

Bibliographic references

Includes bibliographical references and index.

Contents

• GrpE, Hsp110-Grp170, HspBP1/Sil1 and BAG domain proteins: nucleotide exchange factors for Hsp70 molecular chaperones / Andreas Bracher and Jacob Verghese
• Functions of the Hsp90-binding FKBP immunophilins / Naihsuan C. Guy, Yenni A. Garcia, Jeffrey C. Sivils, Mario D. Galigniana and Marc B. Cox
• Hsp70/Hsp90 organising protein (Hop): beyond interactions with chaperones and prion proteins / Swati Baindur-Hudson, Adrienne L. Edkins and Gregory L. Blatch
• Specification of Hsp70 function by type I and type II Hsp40 / Douglas M. Cyr and Carlos H. Ramos
• Cdc37 as a co-chaperone to Hsp90 / Stuart K. Calderwood
• p23 and Aha1 / Alexandra Beatrice Rehn and Johannes Buchner
• UCS proteins: chaperones for myosin and co-chaperones for Hsp90 / Weiming Ni and Odutayo O. Odunuga
• Chaperonin-co-chaperonin interactions / Aileen Boshoff --Co-chaperones of the mammalian endoplasmic reticulum / Armin Melnyk, Heiko Rieger and Richard Zimmermann
• The evolution and function of co-chaperones in mitochondria / Neta Regev-Rudzki, Kip Gabriel and Dejan Bursac
• CHIP: a co-chaperone for degradation by the proteasome / Adrienne L. Edkins
• The role of HSP70 and Its co-chaperones in protein misfolding, aggregation and disease / Emma J. Duncan, Michael E. Cheetham, J. Paul Chapple and Jacqueline van der Spuy.

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ISBN

• 9783319117300 ((hardback : alk. paper))
• 3319117300 ((hardback : alk. paper)

OCLC

890627320

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