Chemokines : methods and protocols / edited by Astrid E. Cardona, Eroboghene E. Ubogu.

Format
Book
Language
English
Published/​Created
New York : Humana Press : Springer, ©2013.
Description
xi, 238 pages : illustrations (some color) ; 26 cm.

Availability

Copies in the Library

Location Call Number Status Location Service Notes
Lewis Library - Lewis Library - Serials (Off-Site) QH506 .M45 1984 vol.1013 Browse related items Request

    Details

    Subject(s)
    Library of Congress genre(s)
    Series
    Summary note
    "Chemokines constitute a large family of structurally similar cytokines that contain a signature of conserved cysteine residues joined by disulfide bridges. Binding of chemokines to specific G protein-coupled receptors followed by downstream signaling defines their biological function. Initially, chemoattraction was the key function linked to chemokines/chemokine receptors; however, in recent years, it has become clear that chemokine ligand-receptor interactions can also modulate cellular activation, survival, and proliferation, among other functions in homeostatic and diseased states. Importantly, major advances in our understanding of chemokine biology have led to chemokine receptors becoming specific therapeutic targets with great potential. In Chemokines: Methods and Protocols, expert researchers provide practical information regarding experimental models and state of the art protocols used to delineate chemokine/chemokine receptor function and their applications in health and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls"--Publisher website.
    Bibliographic references
    Includes bibliographical references and index.
    Contents
    • Fine balance of chemokines during disease : trafficking, inflammation, and homeostasis / Sandra M. Cardona, Jenny A. Garcia, and Astrid E. Cardona
    • Chemokine-dependent signaling pathways in the peripheral nervous system / Eroboghene E. Ubogu
    • Multispectral imaging and automated laser capture microdissection of human cortical neurons : a quantitative study of CXCR4 expression / Jonathan Pitcher ... [et al.]
    • Chemokine receptors and neural stem cells / Meizhang Li
    • Chemokine receptor interactions with virus-like particles / Luigi Buonaguro, Maria Tagliamonte, and Maria Luisa Visciano
    • Chemokine receptor antagonist development / Alexandre Garin ... [et al.]
    • Novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer / Irina Kufareva ... [et al.]
    • Unraveling chemokine and chemokine receptor expression patterns using genetically engineered mice / Simon Yona ... [et al.]
    • Zebrafish as a model to study chemokine function / Eva Kochhan and Arndt F. Siekmann
    • Inflammatory macrophage migration in experimental autoimmune encephalomyelitis / William J. Karpus
    • Visualizing chemokine-dependent T cell activation and migration in response to central nervous system infection / Monica J. Carson and Emma H. Wilson
    • Epigenetic regulation of chemokine/chemokine receptor expression / Anne-Marie Baird, Kenneth J. O'Byrne, and Steven G. Gray
    • Using fluorescent chemokine uptake to detect chemokine receptors by fluorescent activated cell sorting / Laura B. Ford, Chris A.H. Hansell, and Robert J.B. Nibbs
    • Live cell imaging of chemotactic dendritic cell migration in explanted mouse ear preparations / Michele Weber and Michael Sixt
    • Studying extracellular signaling utilizing a glycoproteomic approach : lectin blot surveys, a first and important step / Jing Cao ... [et al.].
    Other format(s)
    Also available in an electronic version.
    ISBN
    • 1627034250 ((alk. paper))
    • 9781627034258 ((alk. paper))
    LCCN
    2013935308
    OCLC
    827083490
    Statement on language in description
    Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage. Read more...
    Other views
    Staff view