LEADER 04092cam a2200361Ma 4500001 9959483063506421 005 20240502044852.0 008 020813s2009 dcuab b 110 0 eng d 020 0309131219 (paper) 020 9780309131216 (paper) 035 (NjP)5948306-princetondb 035 |z(NjP)Voyager5948306 035 (OCoLC)ocn320590041 040 CDX |beng |cCDX |dOCLCQ |dYDXCP |dIXA |dBTCTA |dSCB |dSOI 050 4 QR13 |b.M526 2009 245 00 Microbial evolution and co-adaptation : |ba tribute to the life and scientific legacies of Joshua Lederberg : workshop summary / |crapporteurs, David A. Relman ... [et al.]. 246 3 Tribute to the life and scientific legacies of Joshua Lederberg 260 Washington, DC : |bNational Academies Press, |c2009. 300 xx, 309 p. : |bill. (chielfy col.), col. maps ; |c23 cm. 500 Papers resulting from a public workshop held on May 20-21, 2008. 505 0 Workshop overview -- Appendix: WO-1. Infectious history / Joshua Lederberg -- The life and legacies of Joshua Lederberg -- Reflections on the career of Joshua Lederberg / David A. Hamburg -- Joshua Lederberg remembered / Stephen S. Morse -- The life and impact of a legend-Joshua Lederberg / Adel Mahmoud -- Microbial ecology and ecosystems -- War and peace: humans and their microbiome / David A. Relman -- Deciphering the complex molecular dialogue of symbiosis: Esperanto or polyglot? / Margret McFall-Ngai -- Pathogen evolution -- Bacterial pathogenicity: an historical and experimental perspective / Stanley Falkow -- Evolution of bacterial-host interactions: virulence and the immune overresponse / Elisa Margolis and Bruce R. Levin -- Antibiotic resistance: origins and countermeasures -- Antibiotic resistance and the future of antibiotics / Julian Davies -- Microbial drug resistance: an old problem in need of new solutions / Stanley N. Cohen -- Expanding the microbial universe: metagenomics and microbial community dynamics / Jo Handelsman -- Infectious disease emergence: past, present, and future -- Emerging infections: condemned to repeat? / Stephen S. Morse -- Ecological origins of novel human pathogens / Mark Woolhouse and Eleanor Gaunt -- Genomic evolvability and the origin of novelty: studying the past, interpreting the present, and predicating the future / Jonathan A. Eisen -- Can we predict future trends in disease emergence? / Peter Daszak -- Appendices: A. Agenda -- B. Acronyms -- C. Glossary -- D. Forum member biographies. 520 "Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions." 504 Includes bibliographical references. 650 0 Microorganisms |xEvolution |vCongresses. 650 0 Communicable diseases |vCongresses. |0http://id.loc.gov/authorities/subjects/sh2009120849 650 0 Evolution |vCongresses. |0http://id.loc.gov/authorities/subjects/sh2008103383 650 0 Adaptation (Biology) |vCongresses. |0http://id.loc.gov/authorities/subjects/sh2009113564 700 1 Lederberg, Joshua. |0http://id.loc.gov/authorities/names/n81095967 700 1 Relman, David A. |0http://id.loc.gov/authorities/names/n2005182633 710 2 Institute of Medicine (U.S.). |bForum on Microbial Threats. |0http://id.loc.gov/authorities/names/n2004120228 902 amt |bm |6a |7m |dv |f1 |e20091013 904 cjf |bo |hm |cb |e20090925 914 (OCoLC)ocn320590041 |bOCoLC |cmatch |d20240501 |eprocessed |f320590041