Details

Subject(s)

• Clinical biochemistry [Browse]
• Metabolism—Disorders [Browse]

Author

De la Iglesia, F. A. [Browse]

Series

Routledge Revivals [More in this series]

Summary note

First published in 1986: This book is to help medical, pharmacy, and advanced students in science to understand the growing importance of continuously advancing biochemical concepts in human disease.

Source of description

Description based on print version record.

Language note

In English.

Contents

• Cover
• Title Page
• Copyright Page
• Preface
• The Authors
• Introduction
• Basic Reference Books
• Table of Contents
• Dedication
• Chapter 1: Abnormalities of Water and Electrolyte Metabolism
• I. Introduction
• II. Water Metabolism
• A. Content
• B. Metabolism and Regulation
• III. Sodium Metabolism
• IV. Potassium Metabolism
• V. Acid-Base Metabolism
• A. Intracellular Hydrogen Ion Concentration
• B. Hydrogen Ion Balance
• C. Respiratory Acidosis and Alkalosis
• D. Metabolic Acidosis
• E. Metabolic Alkalosis
• VI. Calcium Metabolism
• VII. Magnesium Metabolism
• VIII. Phosphate Metabolism
• IX. Regulation of Calcium, Magnesium, and Phosphate Metabolism
• X. Assessment of Disturbed Metabolism
• References
• Further Reading
• Chapter 2: Abnormalities of Trace Element Metabolism
• II. Effect of Environment and Homeostasis
• III. Teratologic Effects
• IV. Effects on Endocrine Organs
• V. Effects on Infectious Diseases
• VI. Effects on Cellular Membranes
• VII. Diseases Associated with Selected Elements
• A. Iron
• B. Copper
• C. Zinc
• D. Manganese
• E. Chromium
• F. Selenium
• G. Mercury
• H. Lead
• I. Cobalt
• J. Nickel
• K. Cadmium
• L. Molybdenum
• Chapter 3: Abnormalities of Cellular Organization
• II. Membrane Structure
• A. General
• B. Cytoskeletal Membrane System
• III. Membrane Composition
• A. Proteins
• 1. General
• 2. Molecular Organization of Membrane Proteins
• B. Lipids
• 2. Molecular Organization of Membrane Lipids
• a. Phospholipids
• b. Steroids
• c. Glycolipids
• IV. Membrane Abnormalities in Cell Injury
• A. Diseases of Membrane Transport Mechanism
• 1. Active Transport
• 2. Epithelial Transport
• a. Diseases of Disturbed Transport
• b. Hypophosphatemia.
• c. Tubular Reabsorption Defects
• B. Membrane Abnormalities in Neurological Disorders
• 1. Synaptic Transmission Abnormalities
• 2. Excitable Membrane Abnormalities
• C. Membrane Abnormalities in Metabolic Disorders
• 1. Brush Border Membrane Disorders
• a. Carbohydrate-Related Abnormalities
• b. Amino Acid- and Protein-Related Abnormalities
• c. Renal Tubular Abnormalities
• d. Secondary Brush Border Membrane Disorders
• 2. Platelet Membranes
• 3. Membrane Surface Receptors
• a. Regulation and Disease
• b. Role in Carcinogenesis
• V. Subcellular Organelles
• A. Nucleus
• B. Mitochondria
• 1. Ischemic Injury
• 2. Toxic Injury
• 3. Genetic Diseases
• C. Lysosomes
• 1. Thyroid Lysosomes in Disease
• 2. Lysosomotropic Effects
• D. Endoplasmic Reticulum
• 1. Changes in Diseases
• 2. Protein Synthesis
• 3. Drug Metabolism
• 4. Metabolism of Body Constituents
• 5. Response to Toxic Compounds
• 6. Enzyme Induction
• a. Enzyme Induction during Development
• b. Enzyme Induction and Drug Metabolism
• c. Clinical Importance of Enzyme Induction
• d. Adverse Effects of Enzyme Induction
• e. Enzyme Induction and Toxic Actions
• f. Enzyme Induction and Gene Regulation
• g. Enzyme Induction and Carcinogenesis
• E. Golgi Apparatus
• VI. Carcinogenesis and Cellular Organelles
• A. Structural Changes
• B. Interactions with Nuclear Components
• VII. Interrelationship Between Cellular Organelles
• VIII. Cell Shape Abnormalities
• A. Erythrocyte Disorders
• 1. Deformation of Erythrocyte Shape
• 2. Hereditary Erythrocyte Disorders
• 3. Hemoglobinopathies Affecting Membrane Structure
• 4. Enzyme Deficiencies in Erythrocytes
• B. Muscular Dystrophy
• IX. Radiation Effects on Biomembranes
• A. Effects of Exposure
• B. Molecular Mechanisms of Radiation Damage
• 1. Protein Damage
• 2. Lipid Damage
• 3. Sugar Radiolysis.
• 4. Effects on Membranes
• 5. Damage of Membrane Function
• Glossary
• Appendix: The International System of Units
• Index.

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ISBN

• 0-429-28659-7
• 1-000-88785-5
• 9780429286599

OCLC

• 1357018898
• 1357148881

Doi

10.1201/9780429286599

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