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Princeton University Library Catalog
Computer-aided antibody design / edited by Kouhei Tsumoto and Daisuke Kuroda.
New York, NY : Humana Press, 
xiv, 491 pages : illustrations (chiefly color) ; 26 cm.
Methods in molecular biology (Clifton, N.J.) ; v. 2552.
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Springer protocols (Series)
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Methods in molecular biology, 1064-3745 ; 2552
This volume details state-of-the- art methods on computer-aided antibody design. Chapters guide readers through information on antibody sequences and structures, modeling antibody structures and dynamics, prediction and optimization of biological and biophysical properties of antibodies, prediction of antibody-antigen interactions, and computer-aided antibody affinity maturation and beyond. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computer-Aided Antibody Design aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Includes bibliographical references and index.
Rights and reproductions note
Current copyright fee: GBP19.00 42\0.
Antibody sequence and structure analyses using IMGTª: 30 years of immunoinformatics
Structural Classification of CDR-H3 in Single-Domain VHH Antibodies
Computational modelling of Antibody and T Cell receptor (CDR3 loops)
Molecular dynamics simulation for investigating antigen-antibody interaction
Molecular Dynamics Methods for Antibody Design
Probing antibody dynamics with geometric simulations
PITHA: a webtool to predict immunogenicity for humanized and fully human therapeutic antibodies
Thermal Stability Estimation of Single Domain Antibodies Using Molecular Dynamics Simulations
Assessing and engineering antibody stability using experimental and computational methods
In Silico Prediction Method for Protein Asparagine Deamidation
Structure-based Optimization of Antibody-Based Biotherapeutics for Improved Developability: A Practical Guide for Molecular Modelers
B-cell epitope predictions using computational methods
Computational Epitope Prediction and Design for Antibody Development and Detection
Information-driven antibody-antigen modelling with HADDOCK
Structural modeling of adaptive immune responses to infection
Protein-Protein Interaction Modelling with the Fragment Molecular Orbital Method
Structural Considerations in Affinity Maturation of Antibody-Based Biotherapeutic Candidates
Structure-based affinity maturation of antibody based on double-point mutations
Antibody affinity maturation using computational methods: from an initial hit to small scale expression of optimised binders
Optimizing Antibody-Antigen Binding Affinities with the ADAPT Platform
Using graph-based signatures to guide rational antibody engineering
A computational framework for determining the breadth of antibodies against highly mutable pathogens
Analytical method for experimental validation of computer-designed antibody
Computational analysis of antibody paratopes for antibody sequences in antibody libraries
Bioinformatic Analysis of Natively Paired VH:VL Antibody Repertoires for Antibody Discovery
Analyzing antibody repertoire using next-generation sequencing and machine learning
A computational pipeline for predicting cancer neoepitopes.
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Computer-Aided Antibody Design [electronic resource] / edited by Kouhei Tsumoto, Daisuke Kuroda.