Inhalation toxicology / edited by Harry Salem, Sidney A. Katz.

2nd ed.
Boca Raton, Fla. : CRC/Taylor & Francis, 2006.
1 online resource (1055 p.)


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Summary note
Written by internationally recognized scientists from academic, industrial, and governmental sectors, Inhalation Toxicology, Second Edition details the methods and materials used in the theoretical and applied aspects of inhalation toxicology. The editors emphasize the relationship between the respiratory system and toxicology of inhaled substances and examine methods and measurements for improving our understanding of the basic mechanisms of effects.The book delineates key issues in the field such as regulatory aspects of exposure and testing, testing equipment and methods, biomarkers
Description based upon print version of record.
Bibliographic references
Includes bibliographical references and index.
Language note
  • Front Cover; Preface; Acknowledgments; About the Editors; Contributors; Contents; 1. Inhalation Risk Assessment at the Environmental Protection Agency; 2. The Development and Application of Acute Exposure Guideline Levels for Hazardous Substances; 3. Emergency Response Planning Guidelines (ERPGs); 4. Directed-Flow Aerosol Inhalation Exposure Systems: Applications to Pathogens and Highly Toxic Agents; 5. Low-Level Effects of VX Vapor Exposure on Pupil Size and Cholinesterase Levels in Rats
  • 6. Application of Intratracheal Instillation Exposure to the Etiological Determination of a Pulmonary Disease Outbreak: Nylon Flock as an Example7. The Use of Large Animals in Inhalation Toxicology; 8. Toxic Load Modeling; 9. Inhalation Toxicology and Carcinogenicity Studies of the National Toxicology Program; 10. Toxicology of Fire and Smoke; 11. Toxicogenomics of Low-Level Nerve Agent Vapor Exposure; 12. Respiratory Sensitization; 13. Peripheral Chemosensory Irritation with Particular Reference to Respiratory Tract Exposure
  • 14. Role of Cytokines in Pulmonary Infl ammation and Fibrosis Induced by Inhaled Mineral Particles15. Hormesis: Implications for Risk Assessment; 16. Nasal Toxicology; 17. Effects of Inhaled Toxicants on the Nose and Nasal Function; 18. Toxicokinetics: Deposition, Absorption, Distribution, and Excretion; 19. Mechanistic Determinants and Modeling of the Inhalation Pharmacokinetics of Volatile Organic Chemicals; 20. Inhalation Toxicology of an Irritant Gas-Historical Perspectives, Current Research, and Case Studies of Phosgene Exposure; 21. Inhalation Toxicology of Riot Control Agents
  • 22. Chemical Warfare Agents and Nuclear Weapons23. The Inhalation Toxicology of Chromium Compounds; 24. Safety Assessment of Therapeutic Agents Administered by the Respiratory Route; 25. Nonclinical Pharmacology and Safety Studies of Insulin Administered to the Respiratory Tract; 26. Inhalation Toxicology of Alcohol/Gasoline Fuels-Current Status; 27. Asbestos; 28. The Inhalation Toxicity of Benzene; 29. Carbon Monoxide; 30. Experimental, Clinical, Occupational Toxicology, and Forensic Aspects of Hydrogen Cyanide with Particular Reference to Vapor Exposure
  • 31. The Pharmacology and Toxicology of Inhaled Dusts, Endotoxins, and Glucans32. Fluorocarbon Alternatives-Methodologies for Special Studies and Results; 33. Animal Models for Three Major Cigarette-Smoke-Induced Diseases; 34. The Impact of Active and Passive Exposure to Cigarette Smoke on Maternal and Fetal Health; 35. Health Aspects of Bioaerosols; 36. Emerging Biothreats: Natural and Deliberate; 37. Toxicology Associated with Respiratory Exposures to Fungi (Molds); 38. Inhalation Toxicity of Botulinum Neurotoxin
  • 39. Inhalation Ricin: Aerosol Procedures, Animal Toxicology, and Therapy
  • 0-429-12716-2
  • 1-280-54603-4
  • 9786610546039
  • 1-4200-3730-7
  • 475983558
  • 773198680
  • 10.1201/9781420037302
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