Multiplex biomarker techniques : methods and applications for COVID-19 disease diagnosis and risk stratification / edited by Paul C. Guest.

New York, NY : Humana Press, [2022]
xv, 417 pages : illustrations (some color) ; 26 cm.


Summary note
This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.
Bibliographic references
Includes bibliographical references and index.
  • Multiplex Technologies in COVID-19 Research, Diagnostics, and Prognostics: Battling the Pandemic
  • Multivalent Vaccine Strategies in Battling the Emergence of COVID-19 Variants
  • Challenges of Multiplex Assays for COVID-19 Research: A Machine Learning Perspective
  • Multiplex Quantitative Polymerase Chain Reaction Diagnostic Test for SARS-CoV-2 and Influenza A/B Viruses
  • Multiplex Quantitative Polymerase Chain Reaction Test to Identify SARS-CoV-2 Variants
  • NIRVANA for Simultaneous Detection and Mutation Surveillance of SARS-CoV-2 and Co-Infections of Multiple Respiratory Viruses
  • Quantitative Real-Time RT-PCR Systems to Detect SARS-CoV-2
  • Guidance for SARS-CoV-2 RNA-Based Molecular Assay Analytical Performance Evaluations
  • A Rapid User-Friendly Lab-on-a-Chip Microarray Platform for Detection of SARS-CoV-2 Variants
  • SARS-CoV-2 Host Immunogenetic Biomarkers
  • FnCas9 Editor Linked Uniform Detection Assay for COVID-19-- Mass Spectrometry Multiplexed Detection of SARS-CoV-2
  • Identification of Circulating Biomarkers of COVID-19 Using MALDI-TOF Mass Spectrometry
  • Antibody-Based Affinity Capture Combined with LC-MS Analysis for Identification of COVID-19 Disease Serum Biomarkers
  • Liquid Chromatography Mass Spectrometry Analysis of Peripheral Blood Mononuclear Cells from SARS-CoV-2 Infected Patients
  • Assay of Fatty Acids and Their Role in the Prevention and Treatment of COVID-19
  • Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease
  • Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases
  • Detection of IgG Antibodies to SARS-CoV-2 and Neutralizing Capabilities Using the Luminexª xMAPª SARS-CoV-2 Multi-Antigen IgG Assay
  • Multiplex Testing of the Effect of Statins on Disease Severity Risk in COVID-19 Cases
  • Evaluating the Effects of Curcumin on the Cytokine Storm in COVID-19 Using a Chip-Based Multiplex Analysis-- COVID-19 Detection Using the NHS Lateral Flow Test Kit
  • Evaluation Protocol for SARS-CoV-2 Serological Assays
  • Measurement of Mitochondrial Respiration in Cryopreserved Human Peripheral Blood Mononuclear Cells (PBMCs)
  • Multiplex Testing of Oxidative-Reductive Pathway in Patients with COVID-19 Disease
  • Point-of-Care Device for Assessment of Blood Coagulation Status in COVID-19 Patients
  • COVID-19 and the Assessment of Coenzyme Q10
  • Isolation and Cell Culture of Human Nasopharyngeal Cells: A Model for Testing Immune Response and Antiviral Treatment
  • Machine Learning Approaches to Analyze MALDI-TOF Mass Spectrometry Protein Profiles
  • A Deep Learning Approach to Identify Chest Computed Tomography Features for Prediction of SARS-CoV-2 Infection Outcomes
  • Genomic Surveillance for Monitoring Variants of Concern: SARS-CoV-2 Delta, Omicron, and Beyond.
  • 9781071623947
  • 107162394X
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