Details

Subject(s)

• Nude mouse—Immunology [Browse]
• Immunology—Animal models [Browse]

Series

• Routledge Revivals [More in this series]
• Routledge revivals

Summary note

First published in 1989, Immunology of Nude Mice presents a discussion of the nature of this viable laboratory mutant. This new volume updates all immunological information contained in the sparse literature concerning nude mice. It comprehensively explores some of the fre-quent questions associated with nude mice, such as if the mutant is really athymic or if the thymic defect causes all of the other deviations from brain to gonads. The practical consequences of hairlessness of the mutant are also consid-ered. Illustrated with original photographs and tables doc-umenting novel facts in immunology and physiology of nude mice, this publication is valuable for investigators and stu-dents entering the field.

Notes

Includes index.

Source of description

Description based on print version record.

Contents

• Intro
• Title Page
• Copyright Page
• Preface
• The Author
• Table of Contents
• Chapter 1 Introduction: The Contradictory Mouse
• Chapter 2 The Nude Mutation
• Chapter 3 The Thymic Defect
• I. Introduction
• II. The Derivation of the Epithelial Stroma
• III. Thymic Cysts and Brown Fat
• IV. The Mesenchymal Component
• V. The Essential Defect in the Nude Mouse Thymus
• VI. The Lymphatic Rudiment and the Lymphoid Infiltraton in the Polycystic Organ
• VII. The Thymus of the nu/ + Hybrid
• VIII. Thymic Hormones
• References
• Chapter 4 T Cells
• I. T-Cell Differentiation and Function
• II. The Specificity Pattern of T Cells
• III. Natural Killer and Cytotoxic Cells
• Chapter 5 B Cells and Immunoglobulins
• II. B-Cell Turnover and Differentiation
• III. Antibody Formation
• IV. Tolerance
• V. Polyclonal Activators and Background Immunoglobulins
• Chapter 6 Stem Cells and Connective Tissues
• I. Bone Marrow Stem Cell Potential and Leukocyte Numbers
• II. Connective Tissues
• III. Mast Cells
• Chapter 7 Phagocytic System and Native Resistance
• I. Phagocytic Cells in Ontogeny
• II. Phagocytic Cells in Adult Nude Mice
• Chapter 8 Lymphatic Tissues and Cellular Immune Reactions
• I. Lymphatic Tissues
• II. Cell-Mediated Immune Reactions
• Chapter 9 Hairlessness and Metabolic Compensations
• I. The Skin
• II. Metabolic Rates and Deviations
• Chapter 10 Neuronendocrine Regulations
• I. Endocrine Organs and Functions
• II. Thermogenesis and Neurotransmitters
• III. Central Nervous System and Behavior
• Chapter 11 Nude Gene Transfers and Remutation
• Chapter 12 Conclusions

Show 43 more Contents items

ISBN

• 1-000-08348-9
• 0-429-28179-X

OCLC

1146561667

Statement on responsible collection description

Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage. Read more...