Preformulation studies are the physical, chemical, and biological studies needed to characterize a drug substance for enabling the proper design of a drug product, whereas the effectiveness of a drug product is determined during the formulation studies phase. Though the two disciplines overlap in practice, each is a significantly distinct phase of new drug development. Entirely focused on preformulation principles, this fully revised and updated Handbook of Preforumulation: Chemical, Biological, and Botanical Drugs, Second Edition provides detailed descriptions of preformulation methodologies, gives a state-of-the-art description of each technique, and lists the currently available tools useful in providing a comprehensive characterization of a new drug entity.
Bibliographic references
Includes bibliographical references and index.
Source of description
Description based on print version record.
Contents
Drug discovery trends
Intellectual property
The scope of preformulation studies
Dissociation, partitioning, and solubility
Release, dissolution, and permeation
Solid-state properties
Dosage form considerations in preformulation
Chemical drug substance characterization
Characterization of biopharmaceuticals
Botanical drugs.
ISBN
1-351-58233-X
1-351-58234-8
1-315-09918-7
OCLC
1090539899
Statement on responsible collection description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage. Read more...