Details

Subject(s)

• Toxicology [Browse]

Summary note

Focuses on research procedures in toxicology, aiming to illustrate concepts and types of toxicity from a mechanistic point of view. Examples of chemical intoxicants are used to illustrate mechanisms in each stage of toxicity.

Notes

Description based upon print version of record.

Bibliographic references

Includes bibliographical references (pages 218-247) and index.

Source of description

Description based on print version record.

Language note

English

Contents

• Book Cover; Half-Title; Title; Copyright; Contents; Preface; Acknowledgements; 1 Scope of Toxicology; 2 Stages in the Induction of Toxicity; 3 Kinetics and End-points; 4 Acute and Chronic Intoxication; 5 Delivery of Intoxicant; 6 Delivery of Intoxicant; 6.1 Introduction; 6.2 Bioactivation; 6.3 Delivery of Bioactivated Intoxicants; 6.4 Cytochrome P450s; 6.5 Active Transport of Intoxicants; 6.6 Biliary Excretion and Enterohepatic Circulation; 6.7 Methods to Establish if In Vivo Bioactivation Occurs; 6.8 Discussion; 6.9 Summary; 7 Initiating Reactions with Targets
• 8 Biological Consequences of Initiating Reactions with Targets9 Exposure, Dose and Chemical Structure, Response and Activity, and Thresholds; 10 Selective Toxicity, Animal Experimentation and In Vitro Methods; 11 Biomonitoring; 12 Epidemiology; 13 Environmental and Ecotoxicology; 14 Reflections, Research and Risk; References; Index

ISBN

• 1-135-74467-X
• 0-429-21792-7
• 1-135-74468-8
• 0-203-29028-3
• 1-280-40254-7
• 9786610402540
• 0-203-21121-9

OCLC

• 646840085
• 1000429872

Doi

• 10.4324/9780203211212

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