Gamma-hydroxybutyrate : molecular, functional, and clinical aspects / edited by Godfrey Tunnicliff and Christopher D. Cash.

Format
Book
Language
English
Published/​Created
London ; New York : Taylor & Francis, 2002.
Description
1 online resource (316 p.)

Details

Subject(s)
Related name
Summary note
Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubiquitous inhibitory neurotransmitter. This has opened up a completely new line of research in an effort to establish a function for GHB.Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects has brought together the combined expertise of many of the leading authorities on the biochemistry
Notes
Description based upon print version of record.
Bibliographic references
Includes bibliographical references and index.
Source of description
Description based on print version record.
Language note
English
Contents
  • Book Cover; Half-Title; Title; Copyright; Contents; Figures; Tables; Contributors; Preface; 1. Metabolism and distribution of ? -hydroxybutyrate in the brain; 2. The ?-hydroxybutyrate receptor in the brain; 3. Part of the pharmacological actions of ?-hydroxybutyrate are mediated by GABA B receptors; 4. Membrane transport of ?-hydroxybutyrate; 5. Action of ?-hydroxybutyrate on neuronal excitability and underlying membrane conductances; 6. Regulation of central dopamine by ?-hydroxybutyrate; 8. ?-Hydroxybutyrate and absence seizure activity; 9. Behavioral pharmacology of ?-hydroxybutyrate
  • 10. Therapeutic uses of ?-hydroxybutyrate11. Abuse potential and toxicology of ?-hydroxybutyrate; 12. 4-Hydroxybutyric aciduria; 13. ?-Hydroxybutyrate and oxidative stress; 14. The role of ?-hydroxybutyrate in brain function; Index
ISBN
  • 1-134-49584-6
  • 0-367-39596-7
  • 0-429-21918-0
  • 1-280-02207-8
  • 0-203-30099-8
  • 1-134-49585-4
  • 9786610022076
LCCN
2009659001
OCLC
317362663
Doi
  • 10.1201/b12570
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