Good Research Practice in Non-Clinical Pharmacology and Biomedicine / edited by Anton Bespalov, Martin C. Michel, Thomas Steckler.

Editor
Bespalov, Anton [Browse]
Format
Book
Language
English
Εdition
1st ed. 2020.
Published/​Created
  • Springer Nature 2020
  • Cham : Springer International Publishing : Imprint: Springer, 2020.
Description
1 online resource (X, 423 p. 34 illus., 21 illus. in color.)

Details

Subject(s)
Editor
Series
Summary note
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Source of description
Description based on publisher supplied metadata and other sources.
Language note
English
Contents
  • 1. Quality in Non-GxP Research Environment
  • 2. Guidelines & Initiatives for Good Research Practice
  • 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices
  • 4. General Principles of Preclinical Study Design
  • 5. Resolving the tension between exploration and confirmation in preclinical biomedical research
  • 6. Blinding and Randomization
  • 7. Out of control? Managing baseline variability in experimental studies with control groups
  • 8. Quality of Research Tools
  • 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies
  • 10. Building robustness intro translational research
  • 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research
  • 12. Minimum Information in In Vivo Research
  • 13. A reckless guide to P-values: Local evidence, global errors
  • 14. Electronic Lab Notebooks and Experimental Design Assistants
  • 15. Data storage
  • 16. Design of meta-analysis studies
  • 17. Publishers’ responsibilities in promoting data quality and reproducibility
  • 18. Quality governance in biomedical research
  • 19. Good Research Practice – Lessons from Animal Care & Use
  • 20. Research collaborations and quality in research: foes or friends?
  • 21. Costs of implementing quality in research practice.
ISBN
3-030-33656-5
OCLC
1143621169
Doi
  • 10.1007/978-3-030-33656-1
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