Applying pharmacogenomics in therapeutics / edited by Xiaodong Feng, Hong-Guang Xie.

  • Boca Raton, FL : CRC Press, [2016]
  • ©є℗♭2016
1 online resource


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Summary note
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare-i.e., personalized medicine. Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text: * Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care * Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services * Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases * Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
Bibliographic references
Includes bibliographical references.
Source of description
Online resource; title from PDF title page (EBSCO, viewed January 11, 2016).
  • Chapter 1. Concepts in pharmacogenomics and personalized medicine / Kelly C. Lee, Joseph D. Ma, and Grace M. Kuo
  • chapter 2. Principles of pharmacogenetic biotechnology and testing in clinical practice / Rui Liu, Gary Yuan Gao, and Long Ma
  • chapter 3. Essential pharmacogenomic biomarkers in clinical practice / Cong Liu, Weiguo Chen, and Wei Zhang
  • chapter 4. Applying pharmacogenomics in drug discovery and development / Ruth Vinall
  • chapter 5. Pharmacogenomics and laboratory medicine / Jianbo J. Song
  • chapter 6. Clinical applications of pharmacogenomics in cancer therapy / Mario Listiawan, Max Feng, and Xiaodong Feng
  • chapter 7. Clinical applications of pharmacogenomics in drug therapy of cardiovascular diseases / Tibebe Woldemariam
  • chapter 8. Clinical applications of pharmacogenomics in drug therapy of neurologic and psychiatric disorders / Megan J. Ehret
  • chatper 9. Applying pharmacogenomics in the therapeutics of pulmonary diseases / Wei Zhang and Jason X.-J. Yuan
  • chapter 10. Pharmacogenomics and alternative medicine : merge of future and tradition / Wei Zhang, Xiao-Ping Chen, and Hong-Hao Zhou
  • chapter 11. Pharmacoeconogenomics : a good marriage of pharmacoeconomics and pharmacogenomics / Hong-Guang Xie.
  • 9781466582682 ((electronic bk.))
  • 1466582685 ((electronic bk.))
  • 9780429073298 ((electronic bk.))
  • 0429073291 ((electronic bk.))
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