Molecular biology of parasitic protozoa / edited by Deborah F. Smith and Marilyn Parsons.

Oxford ; New York : IRL Press at Oxford University Press, ©1996.
xvi, 233 pages : illustrations ; 25 cm.


Summary note
Frontiers in Molecular Biology is a series of books designed to report on rapidly evolving, key areas of research in molecular biology. Individual chapters are written by leading researchers who are specialists in their fields. Each book is carefully organized to provide an integrated analysis of current progress in the area covered. Parasitic protozoa cause major infectious diseases of humans and domestic animals. In recent years, new techniques in molecular biology have allowed tremendous advances in our understanding of these parasites. Molecular Biology of Parasitic Protozoa covers this fast-moving field at an advanced level for which there is no other up-to-date book. Topics covered include trypanosomatid and Toxoplasma genetics, structure and replication of kinetoplast DNA, regulation of gene expression in trypanosomes, trans-splicing, RNA editing, the three genomes of Plasmodium, mechanisms of drug resistance, biogenesis of glycosomes and hydrogenosomes, glycosylphosphatidylinositols and the surface architecture of parasitic protozoa. Molecular Biology of Parasitic Protozoa is a unique compendium of current research findings in this important area. It contains over 900 references and provides a comprehensive review of the field as well as valuable insights and predictions of future progress by leading researchers.
Bibliographic references
Includes bibliographical references and index.
  • 1. Introduction / Deborah F. Smith and Marilyn Parsons
  • 2. Trypanosomatid genetics / John Swindle and Andrew Tait
  • 3. The three genomes of Plasmodium / Jean E. Feagin and Michael Lanzer
  • 4. Toxoplasma as a model genetic system / L. David Sibley, Dan K. Howe, Kiew-Lian Wan, Shahid Khan, Martin A. Aslett and James W. Ajioka
  • 5. Kinetoplast DNA: structure and replication / Paul T. Englund, D. Lys Guilbride, Kuo-Yuan Hwa, Catherine E. Johnson, Congjun Li, Laura J. Rocco and Al F. Torri
  • 6. Developmental regulation of gene expression in African trypanosomes / Etienne Pays and Luc Vanhamme
  • 7. Trans-splicing in trypanosomatid protozoa / Elisabetta Ullu, Christian Tschudi and Arthur Gunzl
  • 8. RNA editing: post-transcriptional restructuring of genetic information / Stephen L. Hajduk and Robert S. Sabatini
  • 9. Biogenesis of specialized organelles: glycosomes and hydrogenosomes / Jurg M. Sommer, Peter J. Bradley, C.C. Wang and Patricia J. Johnson
  • 10. Mechanisms of drug resistance in protozoan parasites / Dyann F. Wirth and Alan Cowman
  • 11. Glycosyl-phosphatidylinositols and the surface architecture of parasitic protozoa / Malcolm J. McConville.
  • 019963601X ((pbk.))
  • 9780199636013 ((pbk.))
  • 0199636028 ((hbk.))
  • 9780199636020 ((hardcover))
  • 0199636028 ((hardcover))
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