Skip to search
Skip to main content
Catalog
Help
Feedback
Your Account
Library Account
Bookmarks
(
0
)
Search History
Search in
Keyword
Title (keyword)
Author (keyword)
Subject (keyword)
Title starts with
Subject (browse)
Author (browse)
Author (sorted by title)
Call number (browse)
search for
Search
Advanced Search
Bookmarks
(
0
)
Princeton University Library Catalog
Start over
Cite
Send
to
SMS
Email
EndNote
RefWorks
RIS
Printer
Bookmark
Network medicine : complex systems in human disease and therapeutics / edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman.
Format
Book
Language
English
Published/Created
Cambridge, Massachusetts : Harvard University Press, 2017.
Description
xi, 436 pages : illustrations (chiefly color) ; 25 cm
Availability
Available Online
JSTOR DDA
Copies in the Library
Location
Call Number
Status
Location Service
Notes
Engineering Library - Stacks
R858 .N48 2017
Browse related items
Request
Details
Subject(s)
Medical informatics
[Browse]
Data integration (Computer science)
[Browse]
Diseases
—
Causes and theories of causation
—
Data processing
[Browse]
Therapeutics
—
Data processing
[Browse]
Medicine
—
Data processing
[Browse]
Editor
Loscalzo, Joseph
[Browse]
Barabási, Albert-László
[Browse]
Silverman, Edwin K.
[Browse]
Summary note
"Network medicine, a new field which developed from the application of systems biology approaches to human disease, embraces the complexity of multifactorial influences on disease, which can be driven by non-linear effects and molecular and statistical interactions.The development of comprehensive and affordable Omics platforms provides the data types for network medicine, and graph theory and statistical physics provide the theoretical framework to analyze networks. While network medicine provides a fundamentally different approach to understanding disease etiology, it will also lead to key differences in how diseases are treated--with multiple molecular targets that may require manipulation in a coordinated, dynamic fashion. Much remains to be learned regarding the optimal approaches to integrate different Omics data types and to perform network analyses; this book provides an overview of the progress that has been made and the challenges that remain."-- Provided by publisher
Notes
Includes index.
Bibliographic references
Includes bibliographical references and index.
Contents
Scientific basis of network medicine / Edwin K. Silverman and Joseph Loscalzo
Introduction to network analysis / Jorg Menche and Albert-Laszlo Barabasi
Human interactomes in network medicine / Michael E. Cusick, Benoit Charloteaux, Thomas Rolland, Michael A. Calderwood, David E. Hill, and Marc Vidal
Social networks in human disease / Martin W. Schoen and Douglas Luke
Phenotype, pathophenotype and endo(patho)phenotype in network medicine / Calum A. MacRae
A new paradigm for defining human disease and therapy / Joseph Loscalzo
Complex disease genetics and network medicine / Edwin K. Silverman
Transcriptomics and network medicine / Kimberly Glass and John Quackenbush
Post-translational modifications of the proteome: the example of Tau in the neuron and the brain / Guy Lippens, Jeremy Gunawardena, Isabelle Landrieu, Caroline Smet-Nocca, Sudhakaran Prabakaran, Benjamin Parent, Arnaud Leroy, and I. Huvent
Epigenetics and network medicine / Dawn L. DeMeo and Scott T. Weiss
Metabolomics and network medicine / Jessica Lasky-Su and Clary B. Clish
Using integrative Omics approaches in network medicine / Shuyi Ma, John C. Earls, James A. Eddy, and Nathan D. Price
Cancer network medicine / Takeshi Hase, Samik Ghosh, Sucheendra K Palaniappan, and Hiroaki Kitano
Systems pharmacology in network medicine / Edwin K. Silverman and Joseph Loscalzo
Systems approaches to clinical trials / Elliott M. Antman
Microbiomics in network medicine / Joanne E. Sordillo, George M. Weinstock, and Augusto A. Litonjua.
Show 13 more Contents items
ISBN
9780674436534 ((hbk. ; : alk. paper))
0674436539 ((hbk. ; : alk. paper))
LCCN
2016006644
OCLC
939597214
Statement on language in description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage.
Read more...
Other views
Staff view
Ask a Question
Suggest a Correction
Report Harmful Language
Supplementary Information
Other versions
Network medicine : complex systems in human disease and therapeutics / edited by Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman.
id
99125427513406421
Network medicine : complex systems in human disease and therapeutics / edited By Joseph Loscalzo, Albert-László Barabási, Edwin K. Silverman.
id
SCSB-10553168