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Hallelujah moments : tales of drug discovery / Eugene H. Cordes.
Author
Cordes, Eugene H.
[Browse]
Format
Book
Language
English
Published/Created
Oxford : Oxford University Press, [2014]
Description
xiv, 243 pages : illustrations some color ; 24 cm
Availability
Available Online
Ebook Central Perpetual, DDA and Subscription Titles
Copies in the Library
Location
Call Number
Status
Location Service
Notes
Firestone Library - Stacks
RM301.25 .C67 2014
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Details
Subject(s)
Drug development
—
History
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Drugs
—
Research
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Pharmaceutical chemistry
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Library of Congress genre(s)
History
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Summary note
"Drug discovery in the pharmaceutical industry has important consequences for the health and wellbeing of people everywhere. However, the general public knows little about the paths through which basic research findings are translated into products that protect or restore human health: the route from the laboratory bench to the bedside. In Hallelujah Moments, Eugene Cordes reveals how some of the most important and influential drugs have been brought into the practice of clinical medicine through the wit and determination of scientists in academia and industry. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career in both the academic and industrial settings. These tales are "adventure stories," and they trace the route of important drugs like Januvia, Primaxin, Capoten, and Zocor from concept to the clinic. Cordes shows us the dynamic and critical thinking needed to create a drug that meets important health needs. These are human stories of imagination, risk-taking, problem-solving, and perseverance. Written accessibly for a non-scientist audience, Hallelujah Moments provides insights into the fascinating world of drug discovery like never before."-- Book jacket.
Bibliographic references
Includes bibliographical references (pages 229-236) and index.
Contents
Seduced by drug discovery
The small molecules of life
Proteins : molecular wonders in three dimensions
Proteins perform multiple functions : enzymes, receptors, ion channels
Drug discovery and development : the road from an idea to promoting human health
Finasteride : the Gary and Jerry show
Basic research, snake venoms, and ACE inhibitors : Ondetti, Cushman, and Patchett
Statins : protection against heart attacks and strokes
The perils of primaxin
Avermectins : molecules of life battle parasites
Fludalanine : nice try but no hallelujah
Diabetes breakthrough : Januvia and Janumet.
Show 9 more Contents items
ISBN
9780199337149 ((alk. paper))
0199337144 ((alk. paper))
LCCN
2013023203
OCLC
847936903
Statement on language in description
Princeton University Library aims to describe library materials in a manner that is respectful to the individuals and communities who create, use, and are represented in the collections we manage.
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Hallelujah moments : tales of drug discovery / Eugene H. Cordes.
id
99125350225306421
Hallelujah moments : tales of drug discovery / Eugene H. Cordes.
id
SCSB-9102238